Clinical Investigation of the Physiologic Disposition of a Phthalanilide (nsc-38280) and a Phthalamidine Derivative (nsc-57155) in 7 Patients.
نویسندگان
چکیده
thalanilides (10) in animals (2—7, 9, 13, 15, 20, 21, 24, 28— 31, 33, 34) and tissue culture (12, 23, 32),@clinical trial of these compounds has been described by various investi gators (16—18,22). This report deals with the absorption and excretion of the radioactivity of C'4-labeled 4' ,4―bis(2-imidazolin-2-yl) 2-chloroterephthalanilide dihydro chloride (NSC-38280)4 after P.O. and I.V. administration, and with the excretion of C'4-labeled N , N―-bis[p-(N' methylamidino)phenyl]terephthalamidine tetrahydro chloride (NSC-57155)4 after I.V. injection. The chemical
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عنوان ژورنال:
- Cancer research
دوره 25 شماره
صفحات -
تاریخ انتشار 1965